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dietary supplements and drugs that contain
ephedra can injure your health
Drugs and
Their Effects
The FDA sought comments on these issues and is again looking at a
proposed rule entitled "Dietary Supplements Containing Ephedrine Alkaloids."
This rule would require a warning statement for these products, as
well as restrictions on their potency and composition.
The FDA has sent over two dozen warning letters to
companies that market dietary supplements containing ephedrine alkaloids.
These letters are targeted particularly at products that make claims about
improved athletic performance. the letters stress that any claims that their
products make about the effects on the structure and function of the human
body must be truthful and not misleading. They outline the view in light of
the RAND report that the claims being made are not substantiated by
scientific data, and they direct these firms to submit any data supporting
the claims within 15 days.
The letters also warn firms that they must not make claims
about their products' ability to cure or treat a condition or disease such
as obesity. Under the Federal Food, Drug and Cosmetic Act, unapproved
products making these sorts of claims are unapproved new drugs and
therefore subject to other prompt regulatory actions, including injunctions
against firms and seizures of their products.
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The FDA continues to work closely with the Federal
Trade Commission to make sure that dietary supplement products that contain ephedra do not make
misleading and false claims. "If an advertisement states that a product is
'safe,' the advertiser's must show reliable and competent evidence to prove
the claim," said Timothy J. Muris, Chairman of the Federal Trade Commission.
"Consumers depend on advertising for factual information and deceptive ad
claims can put a consumer's health at risk. This is why the FTC is currently
investigating a number of weight loss products containing ephedra and we
will continue to pursue aggressively marketers making unsubstantiated claims
about product safety or effectiveness."
Proposed a warning label for all ephedra-containing dietary supplements. The proposed label warns about the
risks of serious adverse events, including seizure, heart attack, stroke,
and even death. The label also cautions consumers that the risk may increase with the dose, with strenuous
exercise, and with other stimulants such as caffeine; specifies certain
groups (such as women who are pregnant or breast feeding) who should never
use these products; and lists other conditions, such as diseases and the use
of certain medications, that rule out the use of ephedrine alkaloids.
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"The steps being announced today demonstrate
FDA's commitment to taking
the most effective actions possible under current law, given the state of
the scientific evidence," said Dr. McClellan. "It may be possible to use ephedra safely, in small doses, for some purposes. But in the face of
continued serious adverse events following the use of ephedra, there is a
problem. It is a problem we are determined to fix."
Once the thirty day comment period has ended, FDA will analyze the comments
and publish its findings about the most appropriate approach to help reduce
the risk of using dietary supplement products that contain ephedrine
alkaloids.
Click here to read the first part of this article.
Many physicians feel that some
dietary supplements' should be considered drugs' because they contain
known active ingredients, whereas dietary supplements' have little
or no physiologic effects.
Wadler, who is
attending the ACSM Annual Meeting in St. Louis this week, said that
the subject of steroid use in baseball peaked in 1998, when Mark
McGwire admitted to the use of the testosterone precursor, androstenedione.
The toxicology report on Baltimore Orioles pitching prospect Steve
Bechler released today implicates the use of the herbal supplement ephedra
in his death, and underscores once more the
dangers of ephedra use,
particularly when combined with other risk factors.
An athletic boost in the short
term may mean health problems in the long term for
teens who use
performance-enhancing drugs, warns a youth sports medicine
specialist from the University of Michigan Health System.
Tony La Russa insists that Mark McGuire did not use steroids even after
the slugger, off-camera, told members of a Congressional committee,
"I did steroids."